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compound 12  (Sanofi)

 
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    Structured Review

    Sanofi compound 12
    Compound 12, supplied by Sanofi, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/compound+12/12+compound/pm41052545-143-11-29
    Average 86 stars, based on 1 article reviews
    compound 12 - by Bioz Stars, 2026-10
    86/100 stars

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    Related Articles

    In Vitro:

    Article Title: From Large to Small Cytokine Receptor Antagonists.
    Article Snippet: .. With promising in vitro and in vivo efficacy, the development of Compound 12 stops there for the moment; whether this compound or its derivative will progress as far as Sanofi/UCB’s SAR441566 remains to be seen. ..

    In Vivo:

    Article Title: From Large to Small Cytokine Receptor Antagonists.
    Article Snippet: .. With promising in vitro and in vivo efficacy, the development of Compound 12 stops there for the moment; whether this compound or its derivative will progress as far as Sanofi/UCB’s SAR441566 remains to be seen. ..

    other:

    Article Title: Aurora kinase inhibitor patents and agents in clinical testing: an update (2011 - 2013).
    Article Snippet: Introduction: Aurora kinase A, B and C, members of serine/threonine kinase family, are key regulators of mitosis.. As Aurora kinases are overexpressed in many of the human cancers, small-molecule inhibitors of Aurora kinase have emerged as a possible treatment option for cancer.. Areas covered: In 2009 and 2011, the literature pertaining to Aurora kinase inhibitors and their patents was reviewed.



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    Image Search Results


    BChE binding modes of compounds 12 (a, b), 17 (c, d), and 18 (e, f) in both 2D and 3D configurations.

    Journal: ACS Omega

    Article Title: New Sulfonate-Semicarbazone Hybrid Molecules: Synthesis, Theoretical Evaluations, Molecular Simulations, and Butyrylcholinesterase Inhibition Activity

    doi: 10.1021/acsomega.5c09763

    Figure Lengend Snippet: BChE binding modes of compounds 12 (a, b), 17 (c, d), and 18 (e, f) in both 2D and 3D configurations.

    Article Snippet: Molecular dynamics and binding energy analyses were conducted to evaluate the inhibitory effectiveness of “Compounds 12 , 17 , and 18 ” on the 4DBS protein, using “tacrine” as a reference ligand.

    Techniques: Binding Assay